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Special Interview： Novel Aspects of Mitochondrial Sirtuins
Marcia C. Haigis, Ph.D.
The Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Department of Pathology, Department of Cell Biology, Harvard Medical School
Marcia C. Haigis, Ph.D.
- The Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Department of Pathology, Department of Cell Biology, Harvard Medical School
Dr. Haigis has been studying the functions of mitochondrial sirtuins SIRT3, SIRT4, and SIRT5 in her own lab at Harvard Medical School. During her postdoctoral training in Dr. Guarente’s lab at MIT, Dr. Haigis made a critical discovery that SIRT4 regulates beta cell function through its ADP-ribosyltransferase activity. Now she is revealing fascinating functions of mitochondrial sirtuins in the regulation of metabolism, energy production, and apoptosis. In this interview, Dr. Haigis talks about her exciting research and strategy and also gives helpful advice and encouragement to young scientists, particularly female scientists.
Interviewer：Shuji Hachisuka(Editor of Experimental Medicine, Yodosha,co., Ltd.) , Chihiro Sato, Ph.D. (Washington University School of Medicine)
Streaming Video Clips
HTML5 Version (for iPad/iPhone)
![[DIGEST]](/jikkenigaku/images/washu_digest.gif)
Novel Aspects of Mitochondrial Sirtuins- Marcia C. Haigis, Ph.D.
- 5:00 [November 22nd, 2010]
![[1]](/jikkenigaku/images/washu_number_1.gif)
Sirtuins in mitochondria, the mission as a PI- Marcia C. Haigis, Ph.D.
- 9:50 [November 22nd, 2010]
- The unique features of SIRT3 and SIRT4［6:44］／The mission as a PI of Paul F. Glenn Laboratories［2:28］
![[2]](/jikkenigaku/images/washu_number_2.gif)
The therapeutic potential of mitochondrial sirtuins, a message for female scientists- Marcia C. Haigis, Ph.D.
- 8:13 [November 30th, 2010]
- The therapeutic potential of SIRT3 and SIRT4［2:36］／The key to success as a female scientist［4:13］／Messages for young scientists［0:45］
